Effects of AdalimumabAdalimumab has been studied in several clinical trials for the following conditions.
Clinical studies have shown that adalimumab is effective at improving the symptoms of ankylosing spondylitis, including back pain and morning stiffness. People taking this medication showed greater improvements in their symptoms of ankylosing spondylitis, compared to those not taking it.
Adalimumab was also studied for treating Crohn's disease. In one study, up to 58 percent of those taking the drug showed significant improvement in their Crohn's disease symptoms, compared to just 34 percent of those not taking it. Adalimumab also increased the chance of remission and helped keep the symptoms of Crohn's disease from returning.
Juvenile Idiopathic Arthritis
In studies, children with juvenile idiopathic arthritis who were given adalimumab with or without methotrexate (Rheumatrex®) were less likely to have a disease flare-up, compared to children who were not given adalimumab.
In a study of adalimumab for psoriatic arthritis, adalimumab was shown to reduce pain and other psoriatic arthritis symptoms, including joint stiffness. Also, the medication helped to lessen the physical joint changes of psoriatic arthritis, compared to those not taking it.
In clinical studies looking at adalimumab as a rheumatoid arthritis treatment, the medication was shown to improve the symptoms of rheumatoid arthritis. More of the people taking adalimumab showed improvement, compared to the people not taking it. The medication also improved the physical joint changes that occur with rheumatoid arthritis.