Drug Interactions With Adalimumab

If adalimumab is taken with "live" vaccinations, anakinra, or etanercept, it can cause drug interactions and may lead to problems. Adalimumab drug interactions can cause the body to metabolize the medications differently than intended and can increase your risk of infections or cause you to become infected with the virus or bacteria from the live vaccine.

Adalimumab (Humira)

An Overview of Adalimumab Interactions

Adalimumab (Humira^®) can potentially interact with a few other medicines. Some of the medicines that may lead to drug interactions with adalimumab include:

Anakinra (Kineret^®)
Etanercept (Enbrel^®)
"Live" vaccinations, including:

Chickenpox vaccine (varicella vaccine)
FluMist^® (the nasal vaccine for influenza; the injected vaccine is not live)
MMR vaccine (measles, mumps, rubella vaccine)
Polio vaccine
Rotavirus vaccine
Smallpox vaccine
Yellow fever vaccine
BCG vaccine (used in some countries for tuberculosis).

More Information on Interactions With Adalimumab

The following sections explain in detail the potentially negative interactions that can occur when adalimumab is combined with any of the drugs listed above.

Anakinra (Kineret)

Taking adalimumab with anakinra can increase your risk of getting an infection. In general, these two medications should not be taken together.

Etanercept (Enbrel)

Combining adalimumab with etanercept can increase your risk of getting an infection. In general, these two medications should not be taken together.

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