What Is Adalimumab Used For?

How Adalimumab Works

Adalimumab is part of a class of medicines known as tumor necrosis factor inhibitors, or TNF inhibitors for short. As the name implies, adalimumab blocks the activity of tumor necrosis factor-alpha (TNF-alpha). TNF-alpha is a naturally occurring chemical in the body that is involved in inflammation and other immune system functions.
 
People with rheumatoid arthritis, psoriatic arthritis, psoriasis, ankylosing spondylitis, ulcerative colitis, or Crohn's disease often have higher levels of TNF. These high levels can cause inflammation and lead to problems. By blocking TNF-alpha, adalimumab helps to relieve the symptoms of these conditions and, in some cases, prevents future damage from occurring.
 

Adalimumab Use in Children

Adalimumab is used for treating juvenile idiopathic (rheumatoid) arthritis in children age four and older, but it is not approved for any other use in children. Talk with your healthcare provider about the benefits and risks of using adalimumab in children.
 

Is Adalimumab Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend adalimumab for something other than the conditions discussed in this article. This is called an "off-label" use. At one time, using adalimumab to treat plaque psoriasis or ulcerative colitis were considered off-label uses, and you will still find information on the Internet stating this. However, since adalimumab is now approved for plaque psoriasis and ulcerative colitis, these are no longer off-label uses.
 
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Adalimumab (Humira)

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