Arava Warnings and Precautions

Before starting treatment with Arava, make sure your healthcare provider knows if you have kidney disease, high blood pressure, lung problems, or other medical issues. Other safety precautions with Arava include warnings of potential drug interactions, an increased risk for developing an infection, and the dangers associated with taking this drug while pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Arava® (leflunomide) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • High blood pressure (hypertension)
  • A history of abnormal liver function tests
  • A history of alcoholism or currently drink large amounts of alcohol
  • Blood problems, including anemia or low blood platelets
  • Bone marrow problems
  • A weakened immune system, due to human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), or any other cause
  • Frequent or uncontrolled infections, or currently have an infection
  • Cancer, or a history of cancer
  • Tuberculosis
  • Lung problems
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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