Taking Cataflam With Other Drugs
The following sections explain in detail the potentially negative interactions that can occur when Cataflam is combined with any of the drugs listed above.
Cataflam might reduce the effectiveness of ACE inhibitors for lowering blood pressure and may also increase the risk of kidney damage. If you take Cataflam with an ACE inhibitor, your healthcare provider should monitor your blood pressure to watch for this interaction.
Combining Cataflam with an ARB can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the ARB for lowering blood pressure.
Combining Cataflam with a beta blocker may interfere with the beta blocker's ability to lower blood pressure. Check with your healthcare provider before taking these medications together.
Bile Acid Sequestrants
Bile acid sequestrants can bind to Cataflam in the digestive tract and delay its absorption into the body. To avoid this drug interaction, Cataflam should be taken at least one hour before or four to six hours after the bile acid sequestrant has been taken.
Using corticosteroids with Cataflam can increase the risk of bleeding. Your healthcare provider may choose to monitor you more closely or adjust your dose of these drugs.
Cataflam may increase the level of cyclosporine in the blood, increasing the risk of serious cyclosporine side effects. In addition, this combination may increase the risk of kidney damage. Check with your healthcare provider before taking these medications together.
CYP 2C9 Inducers
The liver breaks down (metabolizes) this medication using certain enzymes known as CYP 2C9 enzymes. Several other medications, known as CYP 2C9 inducers, speed up these enzymes, potentially making Cataflam less effective. Check with your healthcare provider before taking such medications together.