Celebrex Drug Interactions (Cont.)

 
Fluconazole
Taking fluconazole and Celebrex together may cause your body to metabolize the Celebrex differently than intended. Your healthcare provider may choose to start you on a lower dose of Celebrex to avoid this interaction.
 
Furosemide
Taking furosemide and Celebrex together may decrease the effectiveness of furosemide. As a result, your healthcare provider may choose to adjust your doses of these medications as needed.
 
Thiazide Diuretics
Taking a thiazide diuretic and Celebrex together may decrease the effectiveness of the thiazide diuretic. In order to prevent this interaction, your healthcare provider may to adjust your doses as needed.
 
Lithium
Taking lithium and Celebrex together may cause an increase in lithium levels. Your healthcare provider may choose to monitor your lithium levels more closely when either starting or discontinuing Celebrex.
 
Warfarin
If you are taking both Celebrex and warfarin, your body may metabolize the warfarin differently than intended. When starting Celebrex therapy and/or changing your Celebrex dosage, your healthcare provider may choose to monitor your INR (international normalized ratio) more closely and make any necessary adjustments. INR is a test that measures how well your blood is clotting.
 

Final Thoughts on Celebrex Drug Interactions

It is possible that not all of the Celebrex drug interactions were discussed in this article. Therefore, it is important to talk to your pharmacist or healthcare provider about any drug interactions that may apply to you.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;