Additional Drugs That React With Celebrex
Celebrex may increase the level of digoxin in your bloodstream, increasing the risk of dangerous digoxin side effects. If you are taking digoxin, check with your healthcare provider before starting or stopping Celebrex.
Combining Celebrex with a diuretic can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the diuretic.
Taking fluconazole and Celebrex together may increase the level of Celebrex in your blood, possibly increasing the risk of side effects. Your healthcare provider may choose to start you on a lower Celebrex dosage to avoid this interaction.
Taking Celebrex and lithium together may increase the levels of lithium in your body by reducing the kidneys' ability to remove lithium. Your healthcare provider may need to adjust your dose of these drugs and monitor the level of lithium in your blood.
"Blood Thinners" and Other Similar Drugs
Combining Celebrex with anticoagulants ("blood thinners"), antiplatelet drugs, or other medications that increase the risk of bleeding may lead to serious bleeding problems, including dangerous internal bleeding. Do not combine Celebrex with such medications without your healthcare provider's approval and supervision.
Celebrex may increase the risk of methotrexate toxicity. Do not combine these medications without your healthcare provider's supervision and approval.
Probenecid may increase the level of Celebrex in the blood, which increases the risk of Celebrex side effects. Check with your healthcare provider before taking these medications together.