Serious and Rare Reactions to Celebrex

Serious Side Effects

Some Celebrex side effects occur less frequently, but are more serious. These problems include but are not limited to:
  • Cardiovascular problems, including heart attack or stroke
  • Stomach or intestinal problems, including bleeding, ulcers, or a hole (known as a perforation)
  • Liver damage
  • Kidney problems, including kidney failure
  • Fluid retention
  • Swelling of the arms or legs
  • Rapid weight gain
  • Congestive heart failure
  • Allergic reactions (such as a rash, itching, hives, difficulty breathing, or swelling of the mouth or throat).
These possible side effects are a risk with all nonsteroidal anti-inflammatory drugs (NSAIDs) and can lead to life-threatening complications or even loss of life.
(Click Celebrex Precautions and Warnings for more information.)

Rare Celebrex Side Effects

During clinical studies, some side effects occurred in less than 2 percent of people taking Celebrex. Because these side effects are so uncommon, it is difficult to tell whether they were caused by the medication or something else. These possible side effects of Celebrex include but are not limited to:

Final Thoughts on Side Effects With Celebrex

You may experience some or none of the Celebrex side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, tell your healthcare provider if you develop any side effects while taking the drug. Also, let your healthcare provider know if you develop something that "just doesn't seem right." You may not be experiencing a side effect, but your healthcare provider can diagnose and treat the problem.
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