Chondroitin is a
dietary supplement most often used to treat
osteoarthritis, although it is also claimed to be beneficial for a few other uses. It is derived from the cartilage of various animals, including cows and sharks. Chondroitin is often used in combination with
glucosamine, another dietary supplement. The term "chondroitin" almost always refers to chondroitin sulfate.
Chondroitin is a molecule naturally found in the human body (as well as in many animals). It is part of a group of large molecules known as glycosaminoglycans. Researchers believe that chondroitin might work for
arthritis in several ways, such as:
- Inhibiting a cartilage-damaging enzyme known as leukocyte elastase
- Decreasing inflammation (by changing the way certain white blood cells respond to various chemical signals)
- Increasing the production of hyaluronic acid, a component of synovial fluid (the lubricating fluid in joints) and of cartilage.
Effectiveness of Chondroitin
Initial research for this supplement suggested that it might be an effective
arthritis treatment. However, later research has shed some doubt on the effectiveness of chondroitin. At this point, it is not entirely clear if this product really does work for treating arthritis.
Dietary supplements usually lack clear, evidence-based dosing information. However, some information about safe and effective chondroitin dosing can be obtained from clinical studies of the supplement.
Side Effects of Chondroitin
Even though it is a "natural" dietary supplement, chondroitin can cause side effects. Studies have reported various possible side effects, including but not limited to:
(Click Chondroitin Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Chondroitin is probably safe for many people when used appropriately. However, some people may be more likely to experience problems than others. Therefore, you should talk with your healthcare provider before taking chondroitin if you have:
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Chondroitin Safety for more information, including any available warnings and precautions.)
What If I Take an Overdose?
It is not known what exactly to expect from an overdose with chondroitin. If you think you may have taken too much, seek immediate medical attention.
Storage Methods for Chondroitin
Refer to the label of your individual product for information on how best to store the supplement. Keep all medications and supplements out of the reach of children.
