Cod Liver Oil Drug Interactions

When certain medications are taken with cod liver oil, drug interactions could occur. Some of these interactions may increase your risk of bleeding or decrease your blood pressure too much. Medications that can cause negative drug interactions include aspirin, heparin (or heparin-like products) and nonsteroidal anti-inflammatory drugs.

Cod Liver Oil Capsules

An Introduction to Cod Liver Oil Interactions

Even though it is a "natural" product,

cod liver oil can potentially interact with several medicines. These interactions have the potential to be quite serious. Some of the medicines that may lead to cod liver oil drug interactions include:

Medications that "thin" the blood (such as anticoagulant and antiplatelet drugs), such as:
- Antithrombin (ATryn^®, Thrombate III^®)
- Argatroban
- Aspirin (Bayer^® and others)
- Bivalirudin (Angiomax^®)
- Cilostazol (Pletal^®)
- Clopidogrel (Plavix^®)
- Dabigatran etexilate mesylate (Pradaxa^®)
- Dipyridamole (Persantine^®)
- Drotrecogin alfa (Xigris^®)
- Eptifibatide (Integrilin^®)
- Fondaparinux (Arixtra^®)
- Heparin or heparin-like products, including dalteparin (Fragmin^®), enoxaparin (Lovenox^®), or tinzaparin (Innohep^®)
- Lepirudin (Refludan^®)
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

Celecoxib (Celebrex^®)
Diclofenac (Cambia™, Cataflam^®, Flector^®, Solaraze^® Gel, Voltaren^®, Voltaren^® Gel, Voltaren^®-XR, Voltaren Ophthalmic^®, Zipsor™)
Ibuprofen (Motrin^®, Advil^®, Nuprin^®)
Indomethacin (Indocin^®, Indocin SR^®)
Ketoprofen (Orudis^®, Actron^®, Oruvail^®)
Ketorolac (Toradol^®)
Meloxicam (Mobic^®)
Naproxen (Naprosyn^®) or naproxen sodium (Aleve^®, Anaprox^®, Naprelan^®)
Several others (see List of NSAIDs for a more complete list of these medications)

Prasugrel (Effient^®)

Rivaroxaban (Xarelto^®)

Thrombolytics, such as:

Alteplase (Activase^®)
Reteplase (Retavase^®)
Streptokinase (Streptase^®)
Tenecteplase (TNKase^®)

Ticagrelor (Brilinta™)
Ticlopidine (Ticlid^®)

Tirofiban (Aggrastat^®)
Warfarin (Coumadin^®, Jantoven^®)

Vitamin A or vitamin D.

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