The U.S. Food and Drug Administration (FDA) warns that people using NSAIDs, including diclofenac sodium extended-release, may be at higher risk for heart attack or stroke than those who do not take NSAIDs. This warning does not apply to those who take aspirin, however. This risk may be higher in people who have been taking NSAIDs for a long time. These events can occur without warning and can lead to death. Tell your healthcare provider if you have or ever have had any of the following:
Also, tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.