Side Effects With Diclofenac Sodium Extended-Release (Cont.)

Common Side Effects

Diclofenac sodium extended-release has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to side effects that occurred in a similar group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. Based on these studies, the most common side effects with diclofenac sodium extended-release include:
 
  • Stomach pain
  • Constipation
  • Diarrhea
  • Heartburn or indigestion (dyspepsia)
  • Gas
  • Unexplained bleeding
  • Ulcer in the stomach or intestines (peptic ulcer)
  • Nausea
  • Vomiting
  • Anemia
  • Dizziness
  • Swelling
  • Increase in liver enzymes
  • Headache
  • Itching
  • Unexplained rash
  • Ringing in the ears (tinnitus).
     

Rare Side Effects

During clinical studies, rare diclofenac sodium extended-release side effects occurred in less than 1 percent of people taking the drug. Because these side effects are so rare, it is difficult to tell whether they are because of the medication or due to something else. These rare side effects include but are not limited to:
 
(Side Effects With Diclofenac Sodium Extended-Release Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;