Dolobid and Pregnancy

Animal studies indicate that combining Dolobid and pregnancy could possibly harm the fetus, although the drug has not been studied in humans. Therefore, most healthcare providers do not recommend taking it during pregnancy, and the drug should be avoided during the third trimester. If you are taking Dolobid and pregnancy occurs, your healthcare provider will weigh the benefits and risks in your particular situation before making a recommendation.

 

Dolobid and Pregnancy: An Overview

Most healthcare providers do not recommend taking Dolobid® (diflunisal) during pregnancy because it can cause problems for the unborn child or complicate labor and delivery. Taking Dolobid at all during the third trimester should be avoided.
 
Dolobid is considered a pregnancy Category C drug by the U.S. Food and Drug Administration (FDA), which means that it has not been studied in pregnant women. However, when studied in pregnant animals, the drug caused problems for the fetus. This suggests that Dolobid could potentially cause harm to your unborn child. However, it is important to note that animals do not always respond to medicines in the same way that humans do.
 

Dolobid and Pregnancy Category C

The FDA uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that show side effects to the fetus in animal studies but for which no human studies in pregnant women have been done. A pregnancy Category C drug may still be given to a pregnant woman if her healthcare provider believes that its benefits outweigh the possible risks to her unborn child.
 
If you are pregnant or thinking of becoming pregnant while taking Dolobid, let your healthcare provider know. He or she will consider the benefits and risks of Dolobid during pregnancy before making a recommendation for your particular situation.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;