Dolobid Drug Interactions

Some of the drugs that can interact with Dolobid include diuretics, ACE inhibitors, and other nonsteroidal anti-inflammatory drugs. Drug interactions with Dolobid can increase your risk of kidney damage, bleeding, and stomach ulcers, among other things. If drug interactions are a concern in your particular situation, your healthcare provider may adjust your dosages or monitor you more closely.

Dolobid Medicine

An Overview of Dolobid Interactions

Dolobid^® (diflunisal) can potentially interact with a number of medicines. Some of these Dolobid drug interactions include:

Warfarin (Coumadin^®, Jantoven^®)
Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Motrin^®, Advil^®), naproxen (Naprosyn^®), naproxen sodium (Aleve^®, Anaprox^®, Naprelan^®), diclofenac (Cataflam^®, Voltaren^®), indomethacin (Indocin^®), nabumetone (Relafen^®), oxaprozin (Daypro^®), celecoxib (Celebrex^®), meloxicam (Mobic^®), etodolac (Lodine^®), ketoprofen, ketorolac (Toradol^®), and others
Aspirin
Acetaminophen (Tylenol^®)
Lithium (Eskalith^®, Lithane^®, Lithonate^®, Lithotabs^®)
Diuretics, such as torsemide (Demadex^®), furosemide (Lasix^®), and hydrochlorothiazide
ACE inhibitors, such as lisinopril (Zestril^®, Prinivil^®), fosinopril (Monopril^®), captopril (Capoten^®), quinapril (Accupril^®), benazepril (Lotensin^®), enalapril (Vasotec^®), and ramipril (Altace^®)
Angiotensin II receptor blockers (ARBs), including losartan (Cozaar^®), valsartan (Diovan^®), irbesartan (Avapro^®), telmisartan (Micardis^®), and candesartan (Atacand^®)
Methotrexate (Rheumatrex^®, Trexall^™)
Corticosteroids, such as prednisone, hydrocortisone (Cortef^®), dexamethasone (Decadron^®, Dexone^®, Hexadrol^®), and others
Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
Antacids.

Several herbal and nutritional supplements can also interact with Dolobid and may increase the risk of bleeding. Examples of these include but are not limited to:

Dong quai
Feverfew
Garlic
Ginger
Ginkgo biloba
Ginseng
St. John's wort
Fish oil supplements.

(Dolobid Drug Interactions Continued: Page 2)