Dolobid
® (
diflunisal) is a prescription medicine used for mild to moderate pain relief, as well as inflammation or stiffness caused by
osteoarthritis or
rheumatoid arthritis. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs, or
NSAIDs for short.
Brand-name Dolobid was manufactured by Merck & Co., but is no longer being made. Generic versions are still available.
Dolobid and other NSAIDs are thought to work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.
Effects of the Medication
By blocking prostaglandins, Dolobid is useful at reducing pain related to bone, muscle, or tendon injury or inflammation, as well as alleviating pain and joint swelling associated with different
types of arthritis. Dolobid is not a cure for
arthritis, however, nor does it affect the progression of the disease.