Duexis Overdose

Taking too much Duexis (ibuprofen/famotidine) can cause various symptoms, such as vomiting, seizures, or liver problems. Treatment for this type of overdose will usually involve supportive care to treat any symptoms that occur as a result of the overdose. Other possible treatment options may include pumping the stomach, administering activated charcoal, and inducing vomiting.

Can You Take Too Much Duexis?

Duexis™ (ibuprofen/famotidine) is a prescription medication approved to treat osteoarthritis and rheumatoid arthritis. It is a nonsteroidal anti-inflammatory drug (NSAID), combined with an acid reducer medication. As with most medications, it is possible to take too much Duexis.
 
The specific effects of a Duexis overdose can vary, depending on a number of factors, including the dosage and whether it was taken with any other medications or substances.
 

Effects of an Overdose

Based on information from oral overdoses of ibuprofen or famotidine, the following Duexis overdose symptoms might occur:
 
  • Nausea and vomiting
  • Difficulty breathing
  • Dizziness
  • Excessive sleepiness
  • Seizures
  • Liver problems
  • Kidney failure (renal failure)
  • Coma
  • Restlessness
  • Low blood pressure (hypotension) or high blood pressure (hypertension)
  • A rapid heart rate (tachycardia) or a slow heart rate (bradycardia).
 
To avoid the risk of an accidental overdose, make sure to keep Duexis and all other medications out of the reach of children and pets.
 

Treatment for a Duexis Overdose

The treatment for a Duexis overdose will vary.
 If the overdose was recent, a healthcare provider may administer certain medicines to induce vomiting or place a tube into the stomach to "pump the stomach." Activated charcoal may be given to limit absorption of the medication.
 
Treatment will also involve supportive care, which consists of treating any overdose symptoms that occur, such as high blood pressure.
 
It is important that you seek medical attention immediately if you believe that you or someone else may have overdosed on this medication.
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
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