Enbrel Indications

Enbrel^® (etanercept) is a type of tumor necrosis factor (TNF) inhibitor that works by blocking the action of TNF, a chemical in the body. This chemical is known to play a role in inflammation and other immune system reactions. This means that Enbrel is indicated for people with plaque psoriasis, rheumatoid arthritis, and ankylosing spondylitis, which are autoimmune diseases.

When used to treat rheumatoid arthritis, Enbrel is often combined with methotrexate (Rheumatrex^®). Using these two medications together improves the effectiveness of Enbrel. It is also approved for the treatment of moderate-to-severe polyarticular juvenile rheumatoid arthritis ("polyarticular" means that the condition affects five or more joints).

Keep in mind that while clinical studies and actual use of the drug indicate that Enbrel is highly effective for these and other conditions, it is not a cure. Treatment is typically a lifelong process.

(Click Enbrel Uses for more information on conditions this medication can treat, exactly how it works to relieve various symptoms, its use in children, and off-label indications.)