Etodolac Side Effects

Common etodolac side effects include dizziness, stomach pain, or indigestion. A small percentage of people may experience rare side effects while taking the medicine, such as high blood pressure, congestive heart failure, dry mouth, or increased liver enzymes. If you experience serious etodolac side effects, such as unexplained weight gain or blood in your urine, be sure to seek immediate medical attention.

 

An Introduction to Etodolac Side Effects

As with any medicine, side effects are possible with etodolac (Lodine®), but not everyone who takes the drug will experience problems. In fact, most people tolerate etodolac quite well. If side effects do occur, in many cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Up to 10 percent of people stopped taking etodolac because of side effects.
 
(The etodolac side effects discussed below are not a complete list of reported side effects. Your healthcare provider can discuss a more complete list with you.)
 

Common Etodolac Side Effects

Etodolac has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to those that occurred in a similar group of people not taking the medicine. Based on these studies, the most common etodolac side effects (occurring in more than 3 percent of people) included:
 
  • Heartburn or indigestion (dyspepsia)
  • Stomach pain
  • Diarrhea
  • Gas
  • Nausea
  • Dizziness
  • Tiredness or weakness.
     
Other side effects occurring in more than 1 percent of people and thought to be related to etodolac included but were not limited to:
 
  • Constipation
  • Unexplained bleeding
  • Black, tarry stools
  • Changes in stools
  • Vomiting
  • Anemia
  • Fatigue
  • Depression
  • Nervousness
  • Pain with urination (dysuria)
  • Increased need to urinate
  • Itching
  • Unexplained rash
  • Ringing in the ears (tinnitus)
  • Blurred vision.
     
(Etodolac Side Effects Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;