Drugs That Interfere With Gengraf

More Detail on Gengraf Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when Gengraf is combined with any of the drugs listed above.
Gengraf can increase the amount of aliskiren in your blood, possibly increasing your risk for side effects. These medicines should not be taken together.
Allopurinol may increase the level of Gengraf in your blood, potentially increasing your risk for side effects. Do not take these medicines together without first talking to your healthcare provider.
Certain Blood Pressure Medicines
Taking Gengraf with an angiotensin-converting enzyme (ACE) inhibitor could increase your risk for kidney problems, especially if you are dehydrated, which could happen if you do not consume enough fluids. Taking Gengraf with a calcium channel blocker may increase blood levels of both medications. Therefore, talk with your healthcare provider before taking Gengraf with an ACE inhibitor or calcium channel blocker medication.
Combining Gengraf with colchicine can increase the amount of colchicine in your body, increasing your risk for potentially serious colchicine side effects. Talk to your healthcare provider before taking these medicines together. You may need a lower colchicine dosage.
CYP 3A4 Inducer Medications
The body breaks down Gengraf using enzymes in the liver known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Thus, combining Gengraf with one of these drugs may decrease the level of Gengraf in your body, potentially making it less effective. Your healthcare provider may need to monitor you more closely if you take these medicines together.
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Gengraf Drug Information

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