Treating Psoriasis and Rheumatoid Arthritis With Gengraf

Using Gengraf to Treat Psoriasis

Psoriasis is a chronic skin disease that causes areas of red, irritated skin. The condition is believed to occur when the immune system mistakes skin cells for foreign substances, leading to inflammation and rapid turnover of skin cells. As a result of this rapid turnover, dead skin cells build up on the surface of the skin.
There are several different kinds of psoriasis (see Types of Psoriasis). The most common is called plaque psoriasis. People with this type develop thick, red patches of skin that are covered by silvery scales. Theses patches of skin, or plaques, usually develop on the elbows and knees, but can occur anywhere on the body.
Gengraf is approved to treat severe (extensive or disabling) plaque psoriasis in people who otherwise have normal immune systems. It is only approved for use after at least one other treatment has failed, or in people who cannot take other medicines for their psoriasis.
Gengraf improves the symptoms of psoriasis, but will not cure the condition. As with other treatments, your psoriasis symptoms will likely return 4 to 16 weeks after you stop taking Gengraf.

Treating Rheumatoid Arthritis With Gengraf

Rheumatoid arthritis is a chronic, inflammatory disease. It is also an autoimmune disease, which is a type of disease that occurs when the body's immune system sees healthy body tissue as foreign material and attacks it. In rheumatoid arthritis, the immune system attacks the joints, causing pain and inflammation.
Rheumatoid arthritis commonly affects the joints of the fingers, wrists, knees, ankles, and toes. However, other parts of the body can be affected. A distinguishing feature of the disease is that it normally occurs in a symmetrical pattern. This means both sides of the body are equally affected.
The symptoms of rheumatoid arthritis may come and go over time. Most people will experience periods of intense symptoms -- called flares -- alternating with periods where the disease is in remission and symptoms are minimal or nonexistent. As the disease progresses, the joints may become damaged.
(Click Rheumatoid Arthritis Symptoms for more information on signs of this condition.)
Treatment for rheumatoid arthritis is important for reducing pain and slowing down or stopping disease progression. Gengraf is considered a disease-modifying antirheumatic drug (DMARD), which is a class of drugs used to relieve pain and slow down joint damage. Like other DMARDs, it can take several weeks for Gengraf to begin working.
Gengraf is approved to treat severe rheumatoid arthritis that did not adequately respond to methotrexate (Rheumatrex®, Trexall®), another DMARD. It may be used alone or in combination with methotrexate. Gengraf can slow down the progression of rheumatoid arthritis and relieve pain, but it does not cure the disease. Your symptoms will likely return within four weeks after stopping treatment.
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