Initial research (mostly done with glucosamine sulfate) was almost uniformly positive. However, later research has shed some doubt on the effectiveness of glucosamine. At this point, it is not entirely clear if the supplement really does work for arthritis.
(Click Does Glucosamine Work? for more information.)
Dietary supplements usually lack clear, evidence-based dosing information. However, the recommended dose for glucosamine has been clearly established.
(Click Glucosamine Dosage for more information.)
Most studies show that glucosamine does not cause any more side effects than a placebo (a "sugar pill" with no active ingredients). However, a few side effects may be attributed to it, such as:
(Click Glucosamine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Glucosamine may interact with some medications (see Glucosamine Drug Interactions).