Various Drugs Used for Gout

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
The most common treatment for an acute attack of gout is high doses of nonsteroidal anti-inflammatory drugs (NSAIDs) taken by mouth. NSAIDs reduce the inflammation caused by deposits of uric acid crystals, but have no effect on the amount of uric acid in the body.
 
The NSAIDs most commonly prescribed for gout are:
 
Corticosteroids
Corticosteroids are the other type of medicine most commonly prescribed as a treatment for gout. These medicines either are taken by mouth or injected into the affected joint. Corticosteroids are strong anti-inflammatory hormones.
 
The most commonly prescribed corticosteroid is prednisone. People often begin to improve within a few hours of treatment with a corticosteroid, and the attack usually goes away completely within a week or so.
 
Colchicine
When NSAIDs or corticosteroids do not control symptoms, the healthcare provider may consider using colchicine as part of a gout treatment plan.
 
Colchicine is one of the oldest medicines known to be effective against acute gout. It comes from a common European plant, the autumn crocus. An English clergyman, Sidney Smith, said a century and a half ago that he had only to go into his garden and hold out his gouty toe to the plant to obtain a prompt cure. This may have been an exaggeration, but a rapid response to colchicine suggests that the person does indeed have gout.
 
This medication is most effective when taken within the first 12 hours of an acute attack. Healthcare providers may ask people to take oral colchicine as often as every hour until joint symptoms begin to improve or side effects, such as nausea, vomiting, abdominal (stomach) cramps, or diarrhea, make it uncomfortable to continue the drug.
 
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Information on Gout

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