Ibuprofen and Other Medications

 Ibuprofen is a widely available medication used to treat pain, inflammation, fever, and stiffness associated with several different medical conditions. It comes in many different forms, such as tablets, liquid, and capsules. Brand names include Motrin®, Advil®, Genpril®, and Nuprin®; you can also buy generic ibuprofen.
 
In some cases, ibuprofen and other medications should not be combined. For example, negative drug interactions can occur when ibuprofen is taken with warfarin, aspirin, lithium, and diuretics. The effectiveness of both medicines may be decreased, and your dosages may need to be adjusted as a result if you absolutely have to take these drugs together.
 
In addition, other NSAID medications should not be combined with ibuprofen, as this can increase the risk of potentially dangerous bleeding. The one exception is acetaminophen (Tylenol®). In general, acetaminophen products and ibuprofen products can be taken safely together.
 
(To learn more about combining other medications and ibuprofen, click Ibuprofen Drug Interactions. This article lists other drugs that can react negatively with ibuprofen and how to avoid such problems.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD