For people taking ibuprofen, drug interactions with several different medications may occur. Some of these potential drug interactions with ibuprofen involve medications such as aspirin, lithium, and diuretics. Ibuprofen can also interact with a number of herbal and nutritional supplements to increase your risk of bleeding. Certain ibuprofen drug interactions can increase your risk of stomach ulcers; others may change the way your body metabolizes some medicines, and cause some drugs to be less effective.
Ibuprofen (marketed under brand names such as Motrin®, Advil®, Genpril®, and Nuprin®) can potentially interact with a number of medicines. Some of these drug interactions with ibuprofen include:
Corticosteroids, such as prednisone, hydrocortisone (Cortef®), dexamethasone (Decadron®, Dexone®, Hexadrol®), and many others.
Several herbal and nutritional supplements can also interact with ibuprofen and may increase the risk of bleeding. Examples of these include but are not limited to: