Imuran Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Imuran is combined with any of the drugs listed above.
Allopurinol
Allopurinol inhibits one of the enzymes that helps to remove Imuran from the body. If you take allopurinol and Imuran together, your healthcare provider should reduce your
Imuran dosage to about one-third to one-fourth of the usual dose.
Aminosalicylates
Aminosalicylates can increase the level of Imuran in your blood, potentially increasing the risk of
Imuran side effects. Your healthcare provider may need to decrease your Imuran dosage to prevent this interaction from occurring.
Angiotensin-Converting Enzyme Inhibitors
Combining an ACE inhibitor with Imuran can increase your risk of anemia or leukopenia (low levels of certain white blood cells called leukocytes). Talk to your healthcare provider before taking these medications together.
Sulfamethoxazole and Trimethoprim
Taking Imuran with sulfamethoxazole and trimethoprim can increase your risk of leukopenia. Talk to your healthcare provider before taking these medications together.
Warfarin
Imuran may decrease the effectiveness of warfarin, potentially increasing your risk of blood clots. Your healthcare provider should monitor you closely in this case and adjust your warfarin dosage as necessary.
Final Thoughts on Imuran Drug Interactions
It is possible that not all Imuran drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
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