Drug Interactions With Indomethacin

Before starting indomethacin, tell your doctor about any medicines you may already be taking to help avoid potential drug interactions. With indomethacin, interactions may occur with medications like lithium, warfarin, aspirin, and ibuprofen. Other examples of possible drug interactions involve beta blockers, ACE inhibitors, and diuretics. Indomethacin has also been known to interact with certain herbal and nutritional supplements.

Interactions With Indomethacin: An Introduction

Indomethacin (Indocin®) may interact with a number of other medicines. These interactions may involve medications such as:
 
 
  • Angiotensin II receptor blockers (ARBs), such as:

 

 
 
 
  • Corticosteroids, including (but not limited to):
     
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
 
 
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
 
 
 
Several herbal and nutritional supplements can also interact with indomethacin and may increase the risk of bleeding. Examples of these include, but are not limited to:
 
Top Foods to Fight Inflammation

Indomethacin Drug

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