General Information on Indomethacin

Effects of Indomethacin

It is believed that blocking the effects of prostaglandins is what makes indomethacin useful for reducing pain, inflammation, and joint swelling associated with different forms of arthritis and painful conditions.

When and How Do I Take It?

Some general considerations for when and how to take indomethacin include the following:
  • The medication comes in capsules, oral suspension (liquid), and suppositories. Take the capsules and liquid by mouth. Insert the suppositories into the rectum.
  • You may take indomethacin with a glass of water; taking it with milk or food may prevent stomach upset.
  • If you are taking indomethacin for osteoarthritis or rheumatoid arthritis, it may take several weeks before the medication begins to work to its full potential.
  • Take the lowest effective dose for the least amount of time in order to treat your condition. Doing so will decrease your chances of developing serious side effects associated with indomethacin.
  • Take the medication at the same time each day to maintain an even level in your blood.
  • For indomethacin to work properly, you have to take it as prescribed. This medication will not work if you take it in a different way than your healthcare provider prescribes.

Dosing Information

The dose of indomethacin your healthcare provider recommends will vary, depending on a number of factors, including:
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Dosing With Indomethacin for more information.)
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