Approximately 30,000 to 60,000 children in the United States have juvenile rheumatoid arthritis, the most common type of arthritis that occurs in children 16 years of age and younger. The condition is often characterized by joint swelling and pain, decreased functioning (with the affected joints), unexplained rashes, and spiking fevers. The main goals of juvenile rheumatoid arthritis treatment are to preserve a high level of physical and social functioning and to maintain a good quality of life.