Kineret Drug Interactions

TNF inhibitors and "live" vaccinations should not be used during treatment with Kineret. Drug interactions may occur when the medicines are taken together. These interactions can increase your risk of developing potentially serious infections, and the effectiveness of live vaccines may be decreased. To reduce your chances of Kineret interactions, make sure to tell your healthcare provider about all other medicines you are currently taking.

 

Kineret Drug Interactions: An Overview

Kineret® (anakinra) can potentially interact with a few other medications, especially other medications that affect the immune system. Some of these medicines that may lead to Kineret interactions include:
 
  • "Live" vaccinations, including:
o Chickenpox vaccine (varicella vaccine)
o FluMist (the nasal vaccine for influenza; the injected vaccine is not live)
o MMR (measles, mumps, rubella) vaccine
o Smallpox vaccine
o BCG vaccine (used in some countries for tuberculosis)
  • TNF inhibitors (also known as TNF antagonists), such as:

Kineret Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Kineret is combined with any of the drugs listed above.
 
Live Vaccines
Live vaccines are immunizations that contain live viruses or bacteria. If you receive a live vaccine while taking Kineret, it is possible that you might become infected with the virus or bacteria from the vaccine. Also, Kineret can make live vaccines less effective. You should not receive live vaccinations while taking Kineret.
(Kineret Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;