Kineret Warnings and Precautions

If you have any current infections, any allergies, or a history of hepatitis B or tuberculosis, make sure to let your healthcare provider know before taking Kineret. Warnings and precautions also include watching out for certain drug interactions, using the drug with caution if you are pregnant, and avoiding Kineret if you are allergic to any components of the medicine.

Kineret: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Kineret® (anakinra) if you have:
  • Any disease that weakens the immune system, such as diabetes, cancer, HIV, or AIDS
  • Any current infection
  • Infections that come and go (such as cold sores)
  • Plans to receive vaccinations
  • A history of hepatitis B infection or tuberculosis
  • Exposure to chickenpox or tuberculosis (TB)
  • Any allergies, including allergies to food, dyes, latex, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Kineret

Warnings and precautions to be aware of prior to taking Kineret include the following:
  • Kineret can increase your risk of infections, including serious ones. You should not start this drug if you have an existing infection (even a skin infection). While taking Kineret, tell your healthcare provider right away if you think you may have any type of infection. The medication may not be the best choice for people who get frequent infections. Combining it with certain other medications also increases your risk of dangerous infections.
  • Kineret can cause certain infections (such as hepatitis B or tuberculosis) that have become inactive in the body to become active again. Tell your healthcare provider if you have ever had hepatitis B or tuberculosis before starting treatment.
  • Allergic reactions can occur with Kineret. These reactions include:
    • Rashes
    • Hives
    • Itching
    • Wheezing or difficulty breathing
    • Unusual swelling.
Let your healthcare provider know right away if you think you are having an allergic reaction to Kineret. Also, the needle cover of the syringes contains dry natural rubber, which may cause reactions in people allergic to latex.
  • Kineret can interact with other medications (see Kineret Drug Interactions).
  • Kineret is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not currently known (see Kineret and Pregnancy).
  • It is not known if Kineret passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Kineret and Breastfeeding).
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