Despite the current sterile techniques used for all surgeries, infections are always a possibility after total knee replacement. Infections, however, occur rarely, in one to two out of 100 total knee replacements. Treatment options vary, depending on the location of the infection. Infections can range from minor ones, treated only with antibiotics, with or without a few extra days in the hospital, to major infections, requiring a repeat surgery. If an infection develops within the knee, a repeat surgery may be performed and the implant removed. Furthermore, if the infection cannot be cured, the knee may have to be fused, which results in a lack of knee movement. In extreme cases, an amputation could result if the infection is life-threatening.