Krystexxa Drug Interactions

Although no studies have been done on possible drug interactions with Krystexxa, it is believed that this medication might interact with "PEGylated" medicines. Some of these medications can include Adagen, Cimzia, and Doxil, to name a few. To help avoid potential problems, tell your healthcare provider about any other medications you are taking, including nonprescription drugs and vitamins.

An Overview of Interactions With Krystexxa

Krystexxa® (pegloticase) is a prescription gout medication that is given intravenously (by IV). No drug-interaction studies have been done with Krystexxa.
However, it is theoretically possible that Krystexxa might react with "PEGylated" medications (drug molecules that have been attached to polyethylene glycol polymers). PEGylated medications include:
Krystexxa often stimulates the body to produce a certain type of antibody that might bind to other PEGylated medications. It is unknown what effect (if any) this might have on other PEGylated medications.

Final Thoughts

It is possible that not all drug interactions with Krystexxa were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific interactions that may apply to you. It is always a good idea to give your healthcare provider a complete list of all medications you are taking, including prescription drugs, nonprescription drugs, herbs, and supplements.
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Krystexxa Medication Information

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