Krystexxa Overdose

The specific effects of overdosing on Krystexxa (pegloticase) are unknown. However, an overdose of this medication is unlikely, as it is administered by a healthcare provider and each vial of Krystexxa only contains a single dose. If too much is given, a healthcare provider will likely provide supportive care, which consists of treating the symptoms that occur as a result of the overdose.

Can You Receive Too Much Krystexxa?

Krystexxa® (pegloticase) is a prescription gout medication. It is given intravenously (by IV). As with any medication, it is probably possible to receive too much Krystexxa.
 
The specific effects of a Krystexxa overdose can vary depending on a number of factors, including the Krystexxa dosage and whether it was combined with any other medications or substances.
 
Seek immediate medical attention if you or someone else may have overdosed on this medication.
 

Effects of an Overdose

At this time, the effects of a Krystexxa overdose are unknown. However, an overdose is unlikely, as the drug is administered by a healthcare provider and because an entire vial contains only a single dose. Also, there is only one standard Krystexxa dosage, regardless of age or weight, making it less likely for incorrect dosing to occur.
 
Giving Krystexxa too quickly increases the risk of serious allergic reactions and less serious "infusion reactions." It seems reasonable that an overdose of this drug may also increase the risk of such reactions. Of course, it is reasonable to expect than an overdose could cause any of the usual Krystexxa side effects.
 

Treatment Options

Currently, it is not known exactly how best to treat an overdose with Krystexxa. Therefore, treatment will likely involve supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for a Krystexxa overdose may include:
 
  • Fluids through an intravenous line (IV)
  • Closely monitoring vital signs
  • Other treatments based on the complications that occur.
     
It is important that you seek medical attention immediately if you believe that you may have overdosed on Krystexxa.
 
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Krystexxa Medication Information

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