Lodine XL

Lodine XL is a drug that is used to treat pain, joint swelling, and inflammation caused by various types of arthritis. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Lodine XL comes in the form of a tablet and is available in three different strengths, including 400 mg, 500 mg, and 600 mg. Potential side effects of this drug may include nausea, heartburn or indigestion, and vomiting.

 

What Is Lodine XL?

Lodine® XL (etodolac extended-release) is in a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Lodine XL is used to reduce pain, inflammation, swelling, and/or stiffness caused by juvenile rheumatoid arthritis, osteoarthritis, or rheumatoid arthritis.
 
Lodine XL is not a cure for these types of arthritis, nor does it slow the progression of the disease.
 
(Click Lodine XL Uses for more information on these uses, along with possible off-label uses for Lodine XL.)
 

Who Makes Lodine XL?

Lodine XL is manufactured by Wyeth Pharmaceuticals.
 

How Does Lodine XL Work?

Lodine XL and other NSAIDs work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.
 

Lodine XL Effects

By blocking the effects of prostaglandins, Lodine XL is useful at reducing pain, inflammation, and joint swelling associated with different forms of arthritis.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;