Arthritis Home > Allopurinol Dosage

Dosage for Cancer Patients

The recommended allopurinol dose for preventing high uric acid levels that may result from cancer treatment (such as chemotherapy or radiation) is allopurinol 600 mg or 800 mg daily (split up into two or three smaller doses per day) for two or three days, together with a high intake of fluids.
For treating high uric acid levels in children with cancer, the recommended dose is 300 mg per day (for children age 6 to 10 years old) or 150 mg per day (for children under 6 years old).

Dosage for Calcium Oxalate Kidney Stones

The recommended dose for preventing calcium oxalate kidney stones is 200 mg or 300 mg per day, taken as a single dose or as a few (two or three) smaller doses throughout the day.

General Allopurinol Dosage Information

Some considerations for people taking allopurinol include the following:
  • Allopurinol comes in tablet form. It is usually taken one or more times per day, depending on the dose.
  • It is usually best to take it just after a meal, as this may decrease stomach upset.
  • It is important to drink plenty of fluids while taking allopurinol, to help prevent kidney stones.
  • For the medication to work properly, it must be taken as prescribed. Allopurinol will not continue to work if you stop taking it.
  • If you are unsure about anything related to your dosage or allopurinol dosing in general, please talk with your doctor, nurse, or pharmacist.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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