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Allopurinol is a medication approved to prevent several medical conditions that are caused by high uric acid levels in the body. Specifically, this prescription medication can prevent gout, high uric acid levels caused by cancer treatment, and kidney stones in people who have high uric acid levels. Although most people tolerate allopurinol well, it is not suitable for everyone. Side effects may include rashes, diarrhea, and nausea.

What Is Allopurinol?

Allopurinol (Zyloprim®) is a prescription medication approved to prevent the following conditions:
 
  • Gout
  • High uric acid levels due to cancer treatment
  • Kidney stones in people with high uric acid levels.
  •  
(Click What Is Allopurinol Used For? for more information on what the medication is used for, including possible off-label uses.)
 

Side Effects of Allopurinol

As with any medicine, side effects are possible. However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
 
Some of the common side effects include, but are not limited to:
 
  • Diarrhea
  • Nausea
  • Gout attacks (especially at first)
  • Rashes.
  •  
(Click Allopurinol Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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