Arthritis Home > Azulfidine EN-Tabs

Azulfidine EN-tabs has been approved to treat ulcerative colitis, rheumatoid arthritis, and juvenile rheumatoid arthritis. The prescription medication comes in tablet form, and is usually taken two to six times per day. The dosage that your healthcare provider prescribes will depend on factors such as your age, weight, and other medications you are taking. Possible side effects include loss of appetite, headaches, and vomiting.

What Is Azulfidine EN-Tabs?

Azulfidine EN-tabs® (sulfasalazine delayed-release) is a prescription medication that is used to treat the following conditions:
(Click Azulfidine EN-Tabs Uses for more information, including possible off-label uses.)

Who Makes It?

Azulfidine EN-tabs is manufactured by Pfizer, Inc.

How Does It Work?

Azulfidine EN-tabs belongs to a group of medications called aminosalicylates. It is thought that the medication works by inhibiting the production of inflammatory chemicals in the lining of the colon. It decreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation caused by ulcerative colitis.
It is not fully understood exactly how Azulfidine EN-tabs works for rheumatoid arthritis and juvenile rheumatoid arthritis. However, it is thought to likely work by decreasing inflammation and also by affecting the immune system.
Azulfidine EN-tabs has a special "enteric coating," which prevents the tablets from dissolving until they reach the stomach. This helps prevent stomach irritation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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