Arthritis Home > How Does Colchicine Work?

Colchicine is a medication used to treat and prevent gout attacks. It can also help treat a condition known as familial Mediterranean fever (FMF). But how does colchicine work?
 
For gout attacks, it is thought that colchicine works by limiting inflammation. Specifically, it is thought to inhibit certain inflammatory cells (known as neutrophils) that are responsible for some of the symptoms of gout.
 
Although it is unclear how exactly colchicine works for FMF, it is believed that it also works by inhibiting neutrophils or other inflammatory cells.
 
(For more information on colchicine and how it works, click Colchicine Uses. This article discusses uses of this drug, its safety in children, and off-label uses.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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