Arthritis Home > Dolobid

Dolobid is a nonsteroidal anti-inflammatory drug used to relieve symptoms of osteoarthritis or rheumatoid arthritis, such as pain, inflammation, and stiffness. The drug comes in tablet form and is typically taken twice a day. It works by inhibiting the action of certain hormones (called prostaglandins) that cause inflammation and pain in the body. Common side effects include nausea, stomach pain, and heartburn.

What Is Dolobid?

Dolobid® (diflunisal) is a prescription medicine used for mild to moderate pain relief, as well as inflammation or stiffness caused by osteoarthritis or rheumatoid arthritis. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs for short.
(Click Dolobid Uses for more information on these uses, including possible off-label uses for the drug.)

Who Makes It?

Brand-name Dolobid was manufactured by Merck & Co., but is no longer being made. Generic versions are still available.

How Does Dolobid Work?

Dolobid and other NSAIDs are thought to work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.

Effects of the Medication

By blocking prostaglandins, Dolobid is useful at reducing pain related to bone, muscle, or tendon injury or inflammation, as well as alleviating pain and joint swelling associated with different types of arthritis. Dolobid is not a cure for arthritis, however, nor does it affect the progression of the disease.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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