Arthritis Home > Enbrel Dosage

The recommended dose of Enbrel your healthcare provider prescribes will vary depending on several factors, such as your age, the medical condition you are using Enbrel for, and other medications you may be taking. The dosage comes in an injection form and is taken once or twice a week. You can receive your Enbrel injections at your healthcare provider's office or, in some cases, you can give the injections to yourself at home.

Dosage of Enbrel: An Overview

The dose of Enbrel® (etanercept) your healthcare provider recommends will vary depending on a number of factors, including:
  • Your age
  • The medical condition you are using Enbrel for
  • Other medications you may currently be taking
  • Other medical conditions you may have.
Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis
The dosage of Enbrel for these conditions in adults is Enbrel 50 mg per week. This can be given as a single injection or divided into two 25 mg injections given three or four days apart.
Plaque Psoriasis
The dose of Enbrel for plaque psoriasis is Enbrel 50 mg twice a week (three or four days apart) for the first three months, followed by Enbrel 50 mg once a week. Also, lower starting doses (25 or 50 mg per week) have also been shown to be effective.
Juvenile Rheumatoid Arthritis
For children and teens (age 4 to 17) with juvenile rheumatoid arthritis, the Enbrel dose varies according to weight. The dose is 0.8 mg per kg per week (a little less than 0.4 mg per pound per week), up to 50 mg per week.
Children or teens who weigh 138 pounds or more can use the prefilled syringes or SureClick autoinjectors. However, those who weigh less must get their injections from a multi-use vial. This is because the prefilled syringes and autoinjectors contain too much Enbrel, and there is no way to give a smaller dose with these devices.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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