Arthritis Home > Enbrel Drug Interactions

As with any medication, drug interactions with Enbrel are possible. Taking it with other medications, such as live vaccinations, anakinra, and cyclophosphamide, can potentially lead to problems. Some of these interactions can increase your risk of infections or certain tumors. Therefore, be sure to talk to your healthcare provider about any potential drug interactions that may apply to you.

An Overview of Enbrel Interactions

Enbrel® (etanercept) can potentially interact with many drugs. Some of the drugs that may lead to drug interactions with Enbrel include:
  • "Live" vaccinations, including:

More Information on Interactions With Enbrel

The following sections explain in detail the potentially negative consequences that can occur if Enbrel is combined with any of the drugs listed above.
Live Vaccines
Live vaccines are immunizations that contain live viruses or bacteria. If you receive a live vaccine while taking Enbrel, you might become infected with the virus or bacteria from the vaccine. Also, Enbrel can make live vaccines less effective. You should not receive live vaccinations while taking this medication.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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