Arthritis Home > Glucosamine Drug Interactions

When certain medications are combined with glucosamine, drug interactions could occur. Some of these medications include acetaminophen, warfarin, diabetes medicines, and certain chemotherapy drugs. These drug interactions may result in decreased insulin production, increased risk of bleeding, or reduced effectiveness of the medication, and your medical condition may require more frequent monitoring.

An Introduction to Glucosamine Drug Interactions

Even though it is a natural product, glucosamine can potentially interact with a few medicines. Some of the medicines that may lead to glucosamine drug interactions include:

Glucosamine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when glucosamine is combined with any of the drugs listed above.
There have been reports that adding glucosamine to acetaminophen may reduce the pain-relieving effects of acetaminophen. This is predicted to be more of a problem with glucosamine sulfate, compared with glucosamine hydrochloride or N-acetyl glucosamine. Either way, it is probably a relatively minor drug interaction that should not cause problems for most people.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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