Arthritis Home > Ibuprofen

Ibuprofen is a medication that has been licensed to treat several conditions related to pain, inflammation, fever, and stiffness. Some of these conditions include osteoarthritis, rheumatoid arthritis, and painful menstrual periods. This medication is thought to work by blocking the effects of certain hormones that cause inflammation and pain in the body. It is sold either by itself or combined with other medications for treating the common cold, flu, migraine, and sinus pain. The most common side effects include stomach pain, nausea, and heartburn.

What Is Ibuprofen?

Ibuprofen is a medicine used to reduce mild to moderate pain, inflammation, fever, and/or stiffness. It can also be used to treat osteoarthritis or rheumatoid arthritis symptoms or painful menstrual periods. It is available in both prescription and non-prescription strengths.
Ibuprofen may be used by itself or combined with other medications in several common cold, flu, migraine, and sinus products. These can be used to help relieve common cold symptoms, flu symptoms, or sinus problems, such as fever, aches, and pains.
(Click Ibuprofen Uses for more information on how it may be used, including possible off-label uses.)
Ibuprofen belongs to a class of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs for short. It is available as a generic (see Generic Ibuprofen) and is also sold under a number of brand names, including Motrin®, Advil®, Genpril®, and Nuprin®, as well as combination medicines such as Vicoprofen® (hydrocodone and ibuprofen) and Combunox® (oxycodone and ibuprofen).

How Does It Work?

Ibuprofen and other NSAIDs are thought to work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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