Arthritis Home > Nabumetone

Nabumetone is used to treat pain, inflammation, and other symptoms of osteoarthritis and rheumatoid arthritis. It works by inhibiting the action of certain hormones that cause inflammation and pain in the body. The medication comes in tablet form and is typically taken on a daily basis. Common side effects include diarrhea, stomach pain, and dizziness.

What Is Nabumetone?

Nabumetone (Relafen®) is a prescription medicine used to treat pain, inflammation, swelling, and/or stiffness. It is part of a class of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs for short.

Possible Side Effects

As with any medicine, side effects are possible with nabumetone. However, not everyone who takes the drug will experience side effects. If side effects do occur, in many cases, they are minor, meaning that they require no treatment or are easily treated by your healthcare provider.
Common side effects include:
  • Diarrhea
  • Heartburn or indigestion (dyspepsia)
  • Stomach pain
  • Constipation
  • Gas
  • Nausea
  • Unexplained bleeding
  • Dizziness
  • Dry mouth
  • Headache
  • Itching
  • Unexplained rash
  • Ringing in the ears (tinnitus)
  • Swelling.
(Click Nabumetone Side Effects to learn more, including potentially serious side effects you should report to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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