Available by prescription, Simponi is a medication licensed to treat ankylosing spondylitis and certain other inflammatory conditions. It is injected once a month; you can give yourself the injection or have a healthcare provider or caregiver administer it for you. Possible side effects include high blood pressure and skin redness at the site of the injection.
What Is Simponi?
Simponi™ (golimumab) is a prescription medication approved to treat the following conditions:
Simponi belongs to a group of drugs called tumor necrosis factor (TNF) blockers. There are different types of TNF, and Simponi binds preferentially to TNF-alpha. TNF-alpha is a naturally occurring chemical in the body that is involved in inflammation and other immune system functions.
TNF-alpha can contribute to various diseases by encouraging inflammation. Blocking it helps to decrease the inflammation and to relieve the signs and symptoms of ankylosing spondylitis, psoriatic arthritis, ulcerative colitis, and rheumatoid arthritis.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed November 18, 2009.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed November 18, 2009.
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