Arthritis Home > What Is Sulindac Used For?

Many people wonder, "What is sulindac used for?" This drug is often prescribed for the treatment of pain associated with various forms of arthritis and other bone, muscle, or tendon conditions. The medicine can also be used to reduce fever and alleviate swelling or inflammation. There are off-label uses of the drug as well, such as the treatment of migraines or symptoms of fibromyalgia.

An Overview of Uses for Sulindac

Sulindac (Clinoril®) is a prescription medication that has been licensed to treat several conditions related to pain, inflammation, fever, and stiffness.
Specific uses include the following:

How Does It Work?

Sulindac and other NSAIDs (nonsteroidal anti-inflammatory drugs) are thought to work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins. By blocking the effects of prostaglandins, sulindac is effective in:
  • Reducing pain related to bone, muscle, or tendon injury or inflammation
  • Reducing fever
  • Alleviating pain and joint swelling associated with different forms of arthritis and other conditions.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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