Arthritis Home > Zydone and Breastfeeding

In most cases, Zydone should not be taken while breastfeeding. It contains a narcotic, which could cause significant problems in a nursing infant. The acetaminophen component also passes through breast milk, but should not cause problems. If your healthcare provider recommends this drug while breastfeeding, you may have to pump the milk and throw it away.

Can I Take Zydone While Breastfeeding?

Zydone® (hydrocodone/APAP) contains a narcotic medication. The manufacturer does not recommend that breastfeeding women take this medication, because it is not known if this narcotic passes through breast milk. If you are breastfeeding or are thinking about breastfeeding, talk with your healthcare provider before taking Zydone.

Zydone and Breastfeeding: What Are the Risks?

Zydone contains two different medications: hydrocodone bitartrate (a narcotic) and acetaminophen (Tylenol®, also known as APAP). The acetaminophen component does pass through breast milk, but it is not likely to cause problems (see Tylenol and Breastfeeding).
Until relatively recently, it was unknown if hydrocodone passes through breast milk. However, it is now known that hydrocodone does pass through breast milk. As a narcotic, it could cause significant problems in a nursing infant.
Zydone (or another similar medication) is often prescribed to women for pain immediately after childbirth. In this situation, it is likely that only a little of this medication passes to the baby, since the mother is usually producing only very small amounts of colostrum. However, once the mother's milk "comes in," it may be a good idea to avoid (or at least limit) the use of this medication.
If you are taking this medication while breastfeeding and notice unusual, significant drowsiness, difficulty breathing, or limpness in your child, seek immediate medical attention.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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