Medications That React With Mobic

Combining Mobic with a diuretic can increase the risk of kidney problems, especially in people who already have kidney problems, and can decrease the effectiveness of the diuretic.
Taking Mobic and lithium together may increase the levels of lithium in your body by reducing the kidneys' ability to remove lithium. Your healthcare provider may need to adjust your dose of these drugs and monitor the level of lithium in your blood.
"Blood Thinners" and Other Similar Drugs
Combining Mobic with anticoagulants ("blood thinners"), antiplatelet drugs, or other medications that increase the risk of bleeding may lead to serious bleeding problems, including dangerous internal bleeding. Do not combine Mobic with such medications without your healthcare provider's approval and supervision.
Mobic may increase the risk of methotrexate toxicity. Do not combine these medications without your healthcare provider's supervision and approval.
Probenecid may increase the level of Mobic in the blood, increasing the risk of side effects. Check with your healthcare provider before taking these medications together.
Sodium Polystyrene Sulfonate
Combining sodium polystyrene sulfonate with sorbitol may increase the risk of intestinal necrosis (a potentially fatal problem of the digestive tract). Because Mobic oral suspension (liquid) contains sorbitol, these medications should not be combined.
Combining a selective serotonin reuptake inhibitor (SSRI) or a serotonin-norepinephrine reuptake inhibitor (SNRI) with Mobic may increase the risk of bleeding. Check with your healthcare provider before taking Mobic with an SSRI or SNRI.
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