Mobic Precautions and Warnings (Cont.)

• There are certain other medications that Mobic can interact with (see Mobic Drug Interactions).

• All NSAIDs, including Mobic, have been reported to cause cardiovascular events such as a heart attack or stroke, both of which can result in loss of life. People with cardiovascular disease or who have risk factors for cardiovascular disease appear to be at greater risk.

To decrease the chances of these problems occurring, it is recommended that people take the smallest effective dose for the shortest period of time. Also, call 911 if you notice things such as chest pain, shortness of breath, weakness, and slurring of speech.

• All NSAIDs, including Mobic, may cause or worsen high blood pressure. Mobic should be used with caution in people with known high blood pressure.
   
• All NSAIDs, including Mobic, may cause congestive heart failure or swelling. Make sure to contact your healthcare provider if you notice unexplained weight gain or swelling. Also, Mobic should be used with caution in people with heart failure.
   
• All NSAIDs, including Mobic, have been reported to cause problems in the stomach and intestines, including bleeding (known as gastrointestinal bleeding), stomach ulcers, or holes in the stomach or intestines. These problems can lead to serious complications or even loss of life. Extreme caution should be used if Mobic is prescribed to people with a history of ulcers or gastrointestinal bleeding.

To decrease the chances of these problems occurring, it is recommended that people take the smallest effective dose for the shortest period of time. Make sure to contact your healthcare provider immediately if you experience any signs or symptoms of stomach ulcers or bleeding, including:

 

o Abdominal pain (or stomach pain)

o Indigestion

o Black, tarry stools

o Vomiting blood.

• People taking NSAIDs, including Mobic, can suffer kidney damage. It is more common in the elderly and people with kidney disease, heart failure, or liver problems. It is also more common in those taking diuretics or ACE inhibitors.

   
• Liver damage can occur with people who are taking Mobic. Contact your healthcare provider immediately if you notice things such as nausea, tiredness, lethargy, itchy or yellowing skin, abdominal pain (or stomach pain), or flu-like symptoms.
   
• NSAIDs, including Mobic, have been reported to cause allergic reactions. Seek emergency medical attention immediately if you notice things such as difficulty breathing and swelling of the face and throat while taking Mobic.
   
• In rare cases, people taking Mobic can develop a very serious rash. If you notice an unexplained rash or blisters, fever, or itchy skin, stop taking the Mobic and call your healthcare provider.
   
• If you are an alcoholic or drink alcohol frequently, discuss this with your healthcare provider prior to starting Mobic. Alcohol can affect the way the liver works, indirectly affecting the Mobic.
   
• NSAIDs have been known to cause an increase in liver enzymes. Therefore, it is recommended that you have a blood test that looks at your liver function before starting Mobic and 12 weeks after treatment has started.
   
• Mobic has been known to cause anemia. If you are taking Mobic for an extended amount of time and show signs of anemia, talk with your healthcare provider.
   
• You should not take Mobic with any other NSAIDs, as this may increase your risk of any of the problems discussed above. There are many NSAIDs available with or without a prescription; make sure to read labels carefully. Some examples of NSAIDs include ibuprofen (Motrin^®, Advil^®), naproxen (Aleve^®, Anaprox^®, Naprosyn^®, Naprelan^®), celecoxib (Celebrex^®), ketoprofen (Orudis^®, Oruvail^®), etodolac (Lodine^®, Lodine^® XL), diclofenac (Cataflam^®, Voltaren^®), and others. You can ask your doctor or pharmacist for a complete list of these medications.
   
• Mobic is a pregnancy Category C medicine, meaning that it could potentially cause harm to your unborn child. If you are pregnant, you should take Mobic only if the benefits outweigh the possible risks to your unborn child. Mobic is not recommended for women in the third trimester of pregnancy because it can cause injury and even death to the developing fetus. If you become pregnant while taking Mobic, contact your healthcare provider immediately (see Mobic and Pregnancy for more information).
   
• If you are nursing, it is recommended that you not take Mobic. Therefore, if you are nursing and taking Mobic, discuss with your healthcare provider whether to stop nursing or discontinue the medicine.