Common and Rare Reactions to Nabumetone

Common Side Effects

Nabumetone has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
Based on these studies, the most common side effects of nabumetone include:
  • Diarrhea -- up to 14 percent
  • Heartburn or indigestion (dyspepsia) -- up to 13 percent
  • Stomach pain -- up to 12 percent.
Other side effects occurring in more than 3 percent of people included:
  • Constipation
  • Gas
  • Nausea
  • Unexplained bleeding
  • Dizziness
  • Dry mouth
  • Headache
  • Itching
  • Unexplained rash
  • Ringing in the ears (tinnitus)
  • Swelling.

Rare Side Effects

During clinical studies, there were also some side effects that occurred rarely in people taking nabumetone. These side effects occurred in less than 3 percent of people. It is difficult to tell whether these side effects were caused by the medication or something else. These possible nabumetone side effects include but are not limited to:
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